Ronald R. Watson (auth.), Ronald R. Watson (eds.)'s Alcohol and Hormones PDF

By Ronald R. Watson (auth.), Ronald R. Watson (eds.)

ISBN-10: 1461202434

ISBN-13: 9781461202431

ISBN-10: 1461266785

ISBN-13: 9781461266785

Alcoholism, the oldest addictive ailment, continues to be a major challenge due to its significant ameliorations of many physiological structures. The genetic and neurological origins and mechanisms are complicated and merely in part understood. despite the fact that, it's transparent that alcohol use modifies the creation of so much hormones, without delay and not directly modulating the platforms that hormones keep an eye on. Acute and persistent alcohol intake impacts nearly all mobile capabilities of tissues like mind, liver, immune approach, and reproductive and endocrine organs. The latter have significant regula­ tory roles, affecting many features from improvement to repro­ duction. even though rigidity can additional alter alcohol's results on hormone construction, it considerably reasons so much of alcohol's modi­ fications of the physique to take place through adjustments in hormone construction and secretion. Ronald R. Watson vii participants Michael L. Adams • division of Psychiatry, Washington collage college of drugs, St. Louis, MO Robert A. Anderson, Jr .• Ob/Gyn study, Rush-Presbyterian-St. Luke's clinical heart, Chicago,IL Kasibhatla Bhavani • Molecular Heptology Laboratory, Massachusetts normal medical institution melanoma middle, Harvard clinical university, Charlestown, MA Theodore J. Cicero • division of Psychiatry, Washington college institution of drugs, St.

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M. Frasor, R. A. Anderson, and L. D. Russell (1992) Ethanol impairs secretory activity of Sertoli cells in conventional and bicameral culture. BioI. Reprod. 46(Suppl. 1), 171. I"F. Diamond, L. Ringenberg, D. Macdonald, 1. Barnes, C. S. Hu, G. Duckett, M. Sweetland, and A. Root (1986) Effects of drug and alcohol abuse upon pituitary-testicular function in adolescent males. 1. Adolesc. Health Care 7, 28-33. Opioid-Mediated Control of Neuroendocrine Function Roie of /(, Ji, and £ Receptors Theodore J.

Whether this is, in fact, true is difficult to conclude since, in many of these studies, it is impossible to state whether the probes utilized, at the doses used, had the selecti vity assumed. For example, although morphine and naloxone are the prototypic drugs used in most studies as fl selective compounds, at the typically very high doses generally employed, they have affinity for virtually all opiate receptor subtypes. Similarly, most K agonists and antagonists lose their selectivity at doses often 28 Cicero and Adams used.

D. Griswold, ed. Cache River. Clearwater, FL, pp. 578-610. IlIA. Bellve and W. Zheng (1989) Growth factors as autocrine and paracrine modulators of male gonadal functions. J. Reprod. Fert. 85, 771-793. IJ"A. Bergh, A. A. Bergh, 1. E. Damber, M. Hammar, and G. Selstam (1984) Steroid biosynthesis and Leydig cell morphology in unilaterally cryptorchid rats. Acta Endocrinal. 107,556-562. 137L. A. Dostal, R. E. Chapin, S. A. Stefanski, M. W. Harris, and B. A. Schwetz (1988) Testicular toxicity and reduced Sertoli cell numbers in neonatal rats by di(2-ethylhexyl)phthalate and the recovery of fertility as adults.

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Alcohol and Hormones by Ronald R. Watson (auth.), Ronald R. Watson (eds.)

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